Alita Kongchanagul, Ph.D.
Assistant Professor
Vaccine development through comprehensive viral research.
Tel: 66 (0) 2441-9003 – 7 Ext. 1420
Email: alita.kon
mahidol.edu
Ph.D. (Immunology), Faculty of Medicine Siriraj Hospital, Mahidol University, 2011
B.Biotech Hons. (Microbial Biotechnology), The University of Queensland, 2003
Academic Program(s)
Systems Biosciences
I specialize in immunology, virology, and emerging infectious viral diseases. My research focuses on understanding pathogen-host interactions to enhance our knowledge of immunity and develop practical strategies for detection, control, treatment, and vaccine development.
I work mainly with RNA viruses with special interest in influenza A virus. Apart from conducting basic research to enhance our understanding of virus pathogenesis, my current focus revolves around investigating broadly reactive immunity against influenza through the study of influenza virus hemagglutinin stalk-specific antibody responses.
I am also interested in the receptor binding specificity of influenza A virus and how different hemagglutinins bind to sialic acid-containing receptors, and their implications for pathogenicity and transmissibility across host species. Furthermore, my research interest extends to the development of vaccine candidates against infectious viral diseases, utilizing molecular, cellular and virological techniques to select and develop candidate vaccine strains.
1.Kongchanagul A, Masrinoul P, Boonarkart C, Suptawiwat O, Auewarakul P. Antibody Response to Influenza Hemagglutinin Conserved Stalk Domain after Sequential Immunization with Old Vaccine Strains. Adv Virol. 2024 Feb 13;2024:5691673.
2.Kongchanagul A, Samnuan K, Wirachwong P , Surichan S, Puthavathana P , Pitisuttithum P, Boonnak K. A live attenuated H5N2 prime- inactivated H5N1 boost vaccination induces influenza virus hemagglutinin stalk specific antibody responses. Vaccine. 2020 Jan 22;38(4):852-858.
3.Suptawiwat O, Kongchanagul A*, Boonarkart C, Auewarakul P. H1N1 seasonal influenza virus evolutionary rate changed over time. Virus Res. 2018 May 2;250:43-50.
4.Sirinonthanawech N, Surichan S, Namsai A, Puthavathana P , Auewarakul P , Kongchanagul A*. Titration of individual strains in trivalent live-attenuated influenza vaccine without neutralization. J Virol Methods. 2016 237:154-158.
5.Tan GS, Krammer F, Eggink D, Kongchanagul A, Moran TM, Palese P. A pan- h1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J Virol. 2012 86(11), 6179-6188.
